Poor semen parameters are associated with abnormal methylation of imprinted genes in sperm DNA

• Main Authors: Bing Song (Author), Yujie Chen (Author), Chao Wang (Author), Guanjian Li (Author), Zhaolian Wei (Author), Xiaojin He (Author), Yunxia Cao (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Altered sperm DNA methylation patterns of imprinted genes as well as certain spermatogenesis-related genes has been proposed as a possible mechanism of male subfertility. Some reports suggest that there is an elevated risk of congenital diseases, associated with imprinted genes,...