Bulbospinal nociceptive ON and OFF cells related neural circuits and transmitters

• Main Authors: Bingxue Peng (Author), Yingfu Jiao (Author), Yunchun Zhang (Author), Shian Li (Author), Sihan Chen (Author), Saihong Xu (Author), Po Gao (Author), Yinghui Fan (Author), Weifeng Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The rostral ventromedial medulla (RVM) is a bulbospinal nuclei in the descending pain modulation system, and directly affects spinal nociceptive transmission through pronociceptive ON cells and antinociceptive OFF cells in this area. The functional status of ON and OFF neurons play a pivotal role in...