Identification of a Novel Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase: In Vitro and In Silico Studies

Identification of a Novel Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase: In Vitro and In Silico Studies

The enhancement of cholinergic functions via acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition is considered a valuable therapeutic strategy for the treatment of Alzheimer's disease. This study aimed to evaluate the in vitro effect of ZINC390718, previously filtered using...

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Main Authors: Raquel B. M. de Almeida (Author), Deyse B. Barbosa (Author), Mayra R. do Bomfim (Author), Jéssika A. O. Amparo (Author), Bruno S. Andrade (Author), Silvia L. Costa (Author), Joaquín M. Campos (Author), Jorddy N. Cruz (Author), Cleydson B. R. Santos (Author), Franco H. A. Leite (Author), Mariana B. Botura (Author)
Format: Book
Published: MDPI AG, 2023-01-01T00:00:00Z.
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