The Kappa Opioid Receptor: A Promising Therapeutic Target for Multiple Pathologies

• Main Authors: Martin L. Dalefield (Author), Brittany Scouller (Author), Rabia Bibi (Author), Bronwyn M. Kivell (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Kappa-opioid receptors (KOR) are widely expressed throughout the central nervous system, where they modulate a range of physiological processes depending on their location, including stress, mood, reward, pain, inflammation, and remyelination. However, clinical use of KOR agonists is limited by adve...