Aberrant Gut Microbiome Contributes to Barrier Dysfunction, Inflammation, and Local Immune Responses in IgA Nephropathy

• Main Authors: Yuyan Tang (Author), Yong Xiao (Author), Haidong He (Author), Yifan Zhu (Author), Weiqian Sun (Author), Ping Hu (Author), Xudong Xu (Author), Zhen Liu (Author), Zhaowei Yan (Author), Minggang Wei (Author)
• Format: Book
• Published: Karger Publishers, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Numerous research works have shown that serum Gal-deficient (Gd) IgA1 levels are increased in IgA nephropathy (IgAN) patients and these levels are a dangerous risk factor for IgAN. A relationship between the gut microbiota and IgAN has been reported. Whether the gut microbiota particip...