Pharmacokinetic Modeling of Hydrocortisone by Including Protein Binding to Corticosteroid-Binding Globulin

Background: Patients with adrenal insufficiency are treated with oral hydrocortisone (HC) to compensate for the loss of endogenous cortisol production. Intrinsic imperfections of cortisol replacement strategies in mimicking normal cortisol secretion are the underlying cause of the increased morbidit...

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Bibliographic Details
Main Authors: Eric Rozenveld (Author), Nieko Punt (Author), Martijn van Faassen (Author), André P. van Beek (Author), Daan J. Touw (Author)
Format: Book
Published: MDPI AG, 2022-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available