Safety and efficacy of phosphodiesterase-5 (PDE-5) inhibitors in fetal growth restriction: a systematic literature review and meta-analysis

• Main Authors: Ying Liu (Author), Ella Man-Wai Un (Author), Ying Bai (Author), Man Keong Chan (Author), Luo Xin Zeng (Author), Sut Leng Lei (Author), Junjun Li (Author), Carolina Oi Lam Ung (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Fetal growth restriction (FGR) is associated with a higher risk of perinatal morbidity and mortality, as well as long-term health issues in newborns. Currently, there is no effective medicine for FGR. Phosphodiesterase-5 (PDE-5) inhibitors have been shown in pre-clinical studies to imp...