KCa3.1 Promotes Proinflammatory Exosome Secretion by Activating AKT/Rab27a in Atrial Myocytes during Rapid Pacing

• Main Authors: Dishiwen Liu (Author), Huiyu Chen (Author), Yuntao Fu (Author), Yajun Yao (Author), Shanqing He (Author), Youcheng Wang (Author), Zhen Cao (Author), Xuewen Wang (Author), Mei Yang (Author), Qingyan Zhao (Author)
• Format: Book
• Published: Hindawi-Wiley, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. The aim of this study was to investigate the role of the medium-conductance calcium-activated potassium channel (KCNN4, KCa3.1) in the secretion of proinflammatory exosomes by atrial myocytes. Methods. Eighteen beagles were randomly divided into the sham group (n=6), pacing group (n=6), and...