Dabigatran Potentiates Gemcitabine-Induced Growth Inhibition of Pancreatic Cancer in Mice

• Asıl Yazarlar: Kun Shi (Yazar), Helene Damhofer (Yazar), Joost Daalhuisen (Yazar), Marieke ten Brink (Yazar), Dick J. Richel (Yazar), C. Arnold Spek (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2017-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Pancreatic cancer is one of the most lethal solid malignancies, with few treatment options. We have recently shown that expression of protease activated receptor (PAR)-1 in the tumor microenvironment drives the progression and induces the chemoresistance of pancreatic cancer. As thrombin is...