Inhibition of Renal Tubular Epithelial Mesenchymal Transition and Endoplasmic Reticulum Stress-Induced Apoptosis with Shenkang Injection Attenuates Diabetic Tubulopathy

• Main Authors: Wen-Wen Wang (Author), Ying-Lu Liu (Author), Mei-Zi Wang (Author), Huan Li (Author), Bu-Hui Liu (Author), Yue Tu (Author), Can-Can Yuan (Author), Qi-Jun Fang (Author), Jia-Xin Chen (Author), Jie Wang (Author), Yan Fu (Author), Zi-Yue Wan (Author), Yi-Gang Wan (Author), Wei Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The proximal renal tubule plays a critical role in diabetic kidney disease (DKD) progression. Early glomerular disease in DKD triggers a cascade of injuries resulting in renal tubulointerstitial disease. These pathophysiological responses are collectively described as diabetic tubulopath...