Characterization of the Metabolic Response of <i>Streptomyces clavuligerus</i> to Shear Stress in Stirred Tanks and Single-Use 2D Rocking Motion Bioreactors for Clavulanic Acid Production

• Autores principales: David Gómez-Ríos (Autor), Stefan Junne (Autor), Peter Neubauer (Autor), Silvia Ochoa (Autor), Rigoberto Ríos-Estepa (Autor), Howard Ramírez-Malule (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2019-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

<i>Streptomyces clavuligerus</i> is a gram-positive filamentous bacterium notable for producing clavulanic acid (CA), an inhibitor of β-lactamase enzymes, which confers resistance to bacteria against several antibiotics. Here we present a comparative analysis of the morphological and met...