Polymeric Micelles Formulation of Combretastatin Derivatives with Enhanced Solubility, Cytostatic Activity and Selectivity against Cancer Cells

Polymeric Micelles Formulation of Combretastatin Derivatives with Enhanced Solubility, Cytostatic Activity and Selectivity against Cancer Cells

Combretastatin derivatives is a promising class of antitumor agents, tubulin assembly inhibitors. However, due to poor solubility and insufficient selectivity to tumor cells, we believe, their therapeutic potential has not been fully realized yet. This paper describes polymeric micelles based on chi...

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Main Authors: Igor D. Zlotnikov (Author), Alexander A. Ezhov (Author), Artem S. Ferberg (Author), Sergey S. Krylov (Author), Marina N. Semenova (Author), Victor V. Semenov (Author), Elena V. Kudryashova (Author)
Format: Book
Published: MDPI AG, 2023-05-01T00:00:00Z.
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