Polymeric Micelles Formulation of Combretastatin Derivatives with Enhanced Solubility, Cytostatic Activity and Selectivity against Cancer Cells

• Κύριοι συγγραφείς: Igor D. Zlotnikov (Συγγραφέας), Alexander A. Ezhov (Συγγραφέας), Artem S. Ferberg (Συγγραφέας), Sergey S. Krylov (Συγγραφέας), Marina N. Semenova (Συγγραφέας), Victor V. Semenov (Συγγραφέας), Elena V. Kudryashova (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2023-05-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Combretastatin derivatives is a promising class of antitumor agents, tubulin assembly inhibitors. However, due to poor solubility and insufficient selectivity to tumor cells, we believe, their therapeutic potential has not been fully realized yet. This paper describes polymeric micelles based on chi...