Discovery of DNA aptamers targeting SARS-CoV-2 nucleocapsid protein and protein-binding epitopes for label-free COVID-19 diagnostics

• Main Authors: Suttinee Poolsup (Author), Emil Zaripov (Author), Nico Hüttmann (Author), Zoran Minic (Author), Polina V. Artyushenko (Author), Irina A. Shchugoreva (Author), Felix N. Tomilin (Author), Anna S. Kichkailo (Author), Maxim V. Berezovski (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The spread of COVID-19 has affected billions of people across the globe, and the diagnosis of viral infection still needs improvement. Because of high immunogenicity and abundant expression during viral infection, SARS-CoV-2 nucleocapsid (N) protein could be an important diagnostic marker. This stud...