Next-generation sequencing based detection of germline and somatic alterations in a patient with four metachronous primary tumors

• Main Authors: Madhuri Martin (Author), Joshua K. Sabari (Author), Gulisa Turashvili (Author), Darragh F. Halpenny (Author), Hira Rizvi (Author), Natalie Shapnik (Author), Vicky Makker (Author)
• Format: Book
• Published: Elsevier, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Multiple primary tumors (MPTs) are defined as two or more separate synchronous or metachronous neoplasms occurring in different sites in the same individual. These tumors differ in histology, as well as primary sites from which they arise. Risk factors associated with the occurrence of...