Characteristic of K3 (CpG-ODN) as a Transcutaneous Vaccine Formulation Adjuvant

• Main Authors: Sayami Ito (Author), Sachiko Hirobe (Author), Takuto Kawakita (Author), Mio Saito (Author), Ying-Shu Quan (Author), Fumio Kamiyama (Author), Ken J. Ishii (Author), Mizuho Nagao (Author), Takao Fujisawa (Author), Masashi Tachibana (Author), Naoki Okada (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transcutaneous immunization (TCI) is easy to use, minimally invasive, and has excellent efficacy in vaccines against infections. We focused on toll-like receptor (TLR) ligands as applicable adjuvants for transcutaneous formulations and characterized immune responses. TCI was performed using poke-and...