Mechanical stimuli-induced CCL2 restores adult mouse cells to regenerate hair follicles

• Main Authors: Wang Wu (Author), Wei Zhou (Author), Jingwei Jiang (Author), Mengyue Wang (Author), Jinwei Zhang (Author), Jing Yang (Author), Qu Tang (Author), Huawen Liu (Author), Deming Liu (Author), Wei Xu (Author), Julia Li Zhong (Author), Li Yang (Author), Mingxing Lei (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aged cells have declined regenerative ability when subjected to environmental insult. Here we elucidate the mechanism by which mechanical stimulus induces hair regeneration at the microenvironmental regulation level using the hair plucking and organoid culture models. We observed that the skin cells...