Effects of ticagrelor on the pharmacokinetics of rivaroxaban in rats

• Main Authors: Jia Chong (Author), Hao Chen (Author), Dapeng Dai (Author), Shuanghu Wang (Author), Quan Zhou (Author), Junpeng Liu (Author), You Lü (Author), Hualan Wu (Author), Minghui Du (Author), Feifei Chen (Author), Hui Jiang (Author), Yunfang Zhou (Author), Jiefu Yang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Rivaroxaban and ticagrelor are two common drugs for the treatment of atrial fibrillation and acute coronary syndrome. However, the drug-drug interaction between them is still unknown. Objective To investigate the effects of ticagrelor on the pharmacokinetics of rivaroxaban in rats both in vi...