A Candidate Drug Screen Strategy: The Discovery of Oroxylin A in Scutellariae Radix Against Sepsis via the Correlation Analysis Between Plant Metabolomics and Pharmacodynamics

• Main Authors: Lingyu Han (Author), Yue Yuan (Author), Xinyi Chen (Author), Jian Huang (Author), Guan Wang (Author), Chao Zhou (Author), Jianjian Dong (Author), Na Zhang (Author), Yuxin Zhang (Author), Hang Yin (Author), Yunyao Jiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sepsis is an acute systemic infectious disease with high mortality, which urgently needs more effective treatment. Scutellariae radix (SR), a commonly used traditional Chinese medicine (TCM) for clearing heat and detoxification, contains rich natural products possessing anti-inflammatory activity. I...