Prior drug allergies are associated with worse outcome in patients with idiosyncratic drug-induced liver injury: A machine learning approach for risk stratification

• Main Authors: Hao Niu (Author), Pablo Solis-Muñoz (Author), Miren García-Cortés (Author), Judith Sanabria-Cabrera (Author), Mercedes Robles-Diaz (Author), Rocío Romero-Flores (Author), Elvira Bonilla-Toyos (Author), Aida Ortega-Alonso (Author), José M. Pinazo-Bandera (Author), María R. Cabello (Author), Fernando Bessone (Author), Nelia Hernandez (Author), M. Isabel Lucena (Author), Raúl J. Andrade (Author), Inmaculada Medina-Caliz (Author), Ismael Alvarez-Alvarez (Author)
• Format: Book
• Published: Elsevier, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The impact of prior drug allergies (PDA) on the clinical features and outcomes of patients who develop idiosyncratic drug-induced liver injury (DILI) is largely unknown. We aimed to assess the clinical presentation and outcomes of DILI patients based on the presence or absence of PDA and explore the...