Differential effects of glucose‐dependent insulinotropic polypeptide receptor/glucagon‐like peptide‐1 receptor heteromerization on cell signaling when expressed in HEK‐293 cells

• Main Authors: Bashaier Al‐Zaid (Author), Siby Chacko (Author), Charles Ifeamalume Ezeamuzie (Author), Moritz Bünemann (Author), Cornelius Krasel (Author), Tina Karimian (Author), Peter Lanzerstorfer (Author), Suleiman Al‐Sabah (Author)
• Format: Book
• Published: Wiley, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The incretin hormones: glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1) are important regulators of many aspects of metabolism including insulin secretion. Their receptors (GIPR and GLP‐1R) are closely related members of the secretin class of G‐protein‐...