Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans

• Main Authors: Jennifer A. Smith (Author), Jeremy Raisky (Author), Scott M. Ratliff (Author), Jiaxuan Liu (Author), Sharon L. R. Kardia (Author), Stephen T. Turner (Author), Thomas H. Mosley (Author), Wei Zhao (Author)
• Format: Bog
• Udgivet: BMC, 2019-10-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Abstract Background Epigenetic age acceleration, a measure of biological aging based on DNA methylation, is associated with cardiovascular mortality. However, little is known about its relationship with hypertensive target organ damage to the heart, kidneys, brain, and peripheral arteries. Methods W...