Buprenorphine is a weak dopamine releaser relative to heroin, but its pretreatment attenuates heroin‐evoked dopamine release in rats

• Main Authors: Dominic P. Isaacs (Author), Ryan P. Leman (Author), Thomas J. Everett (Author), Hendrick Lopez‐Beltran (Author), Lindsey R. Hamilton (Author), Erik B. Oleson (Author)
• Format: Book
• Published: Wiley, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aims The United States of America is currently in an opioid epidemic. Heroin remains the most lethal opioid option with its death rate increasing by over 500% in the last decade. The rewarding and reinforcing effects of heroin are thought to be mediated by its ability to increase dopamine c...