A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth
Somatic mutations activating MAPK and PI3K signalling play a pivotal role in both tumours and brain developmental disorders. We developed a zebrafish model of brain tumours based on somatic expression of oncogenes that activate MAPK and PI3K signalling in neural progenitor cells and found that HRASV...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2017-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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