The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma

• Main Authors: Li Destri Giovanni (Author), Santagati Maria (Author), Bertuccio Taschia (Author), Cafiso Viviana (Author), La Cava Piera (Author), Palumbo Giuseppe A (Author), Tandurella Igor (Author), Triberio Patrizio (Author), D'Agostino Vito (Author), Valenti Salvo (Author), Pernagallo Salvo (Author), Tomasello Luisa (Author), Salito Loredana (Author), Statello Luisa (Author), Scalia Marina (Author), Angelica Rosario (Author), Majorana Alessandra (Author), Guglielmino Maria R (Author), Duro Laura R (Author), Barbagallo Davide (Author), Ragusa Marco (Author), Di Pietro Cinzia (Author), Lanzafame Salvatore (Author), Di Raimondo Francesco (Author), Stefani Stefania (Author), Mishra Bud (Author), Purrello Michele (Author)
• Format: Book
• Published: BMC, 2009-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Apoptosis is a critical biological phenomenon, executed under the guidance of the Apoptotic Machinery (AM), which allows the physiologic elimination of terminally differentiated, senescent or diseased cells. Because of its relevance...