Pan-tumor T-lymphocyte detection using deep neural networks: Recommendations for transfer learning in immunohistochemistry

• Main Authors: Frauke Wilm (Author), Christian Ihling (Author), Gábor Méhes (Author), Luigi Terracciano (Author), Chloé Puget (Author), Robert Klopfleisch (Author), Peter Schüffler (Author), Marc Aubreville (Author), Andreas Maier (Author), Thomas Mrowiec (Author), Katharina Breininger (Author)
• Format: Book
• Published: Elsevier, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The success of immuno-oncology treatments promises long-term cancer remission for an increasing number of patients. The response to checkpoint inhibitor drugs has shown a correlation with the presence of immune cells in the tumor and tumor microenvironment. An in-depth understanding of the spatial l...