Calycosin alleviates ferroptosis and attenuates doxorubicin-induced myocardial injury via the Nrf2/SLC7A11/GPX4 signaling pathway

• Main Authors: Quancheng Han (Author), Jingle Shi (Author), Yiding Yu (Author), Huajing Yuan (Author), Yonghong Guo (Author), Xiujuan Liu (Author), Yitao Xue (Author), Yan Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundHeart failure is primarily characterized by damage to the structure and function of the heart. Ferroptosis represents a form of programmed cell death, and studies indicate that it constitutes one of the primary mechanisms underlying cardiomyocyte death in heart failure. Calycosin, a natura...