Potent Nrf2-inducing, antioxidant, and anti-inflammatory effects and identification of constituents validate the anti-cancer use of Uvaria chamae and Olax subscorpioidea

• Main Authors: Temidayo D. Popoola (Author), Stephanie T. Guetchueng (Author), Kenneth J. Ritchie (Author), Olufunsho Awodele (Author), Nicola M. Dempster (Author), Oluyemi Akinloye (Author), Satyajit D. Sarker (Author), Amos A. Fatokun (Author)
• Format: Book
• Published: BMC, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Uvaria chamae (UC) and Olax subscorpioidea (OS) roots are included in traditional anti-cancer remedies and some studies have identified their chemopreventive/chemotherapeutic potential. This study aimed to identify some cellular/molecular mechanisms underlying such potential and...