Pharmacokinetic-Pharmacodynamic Correlation for Meropenem Applied to a Burn Child Using a Bioanalytical Liquid Cromatographic Method

Pharmacokinetic-Pharmacodynamic Correlation for Meropenem Applied to a Burn Child Using a Bioanalytical Liquid Cromatographic Method

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Bioanalytical method for LC meropenem quantification in plasma was described. Good absolute recovery (higher than 90%), adequate linearity (0.2-50.0 μg/mL, r2=0.999), high sensitivity (LOQ: 0.2 μg/mL; LOD: 0.1μg/mL) and acceptable stability were shown. Interday/intraday precisions were 2.3%/2.0% and...

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Main Authors: Silvia R. C. J. Santos (Author), Cristina Sanches-Giraud (Author), Carlindo Vieira Jr (Author), Flávio F. de Souza (Author), David S. Gómez (Author), Edvaldo V. Campos (Author), Rodrigo P. de Azevedo (Author), Marcus C. Ferreira (Author), Jorge W. L. Nascimento (Author)
Format: Book
Published: Formifarma, LDA., 2011-10-01T00:00:00Z.
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