Vancomycin pretreatment attenuates acetaminophen-induced liver injury through 2-hydroxybutyric acid

• Автори: Ningning Zheng (Автор), Yu Gu (Автор), Ying Hong (Автор), Lili Sheng (Автор), Linlin Chen (Автор), Feng Zhang (Автор), Jie Hou (Автор), Weidong Zhang (Автор), Zean Zhang (Автор), Wei Jia (Автор), Houkai Li (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2020-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Liver injury caused by acetaminophen (AP) overdose is a leading public health problem. Although AP-induced liver injury is well recognized as the formation of N-acetyl-p-benzoquinone (NAPQI), a toxic metabolite of AP, resulting in cell damage, emerging evidence indicates that AP-induced liver injury...