Biomimetic carbon monoxide delivery based on hemoglobin vesicles ameliorates acute pancreatitis in mice via the regulation of macrophage and neutrophil activity

• Main Authors: Kazuaki Taguchi (Author), Saori Nagao (Author), Hitoshi Maeda (Author), Hiroki Yanagisawa (Author), Hiromi Sakai (Author), Keishi Yamasaki (Author), Tomohiko Wakayama (Author), Hiroshi Watanabe (Author), Masaki Otagiri (Author), Toru Maruyama (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophages play a central role in various inflammatory disorders and are broadly divided into two subpopulations, M1 and M2 macrophage. In the healing process in acute inflammatory disorders, shifting the production of M1 macrophages to M2 macrophages is desirable, because M1 macrophages secrete pr...