An adaptive method of defining negative mutation status for multi-sample comparison using next-generation sequencing
Abstract Background Multi-sample comparison is commonly used in cancer genomics studies. By using next-generation sequencing (NGS), a mutation's status in a specific sample can be measured by the number of reads supporting mutant or wildtype alleles. When no mutant reads are detected, it could...
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Main Authors: | , , , , , , , , , , , |
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Format: | Book |
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BMC,
2021-12-01T00:00:00Z.
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A1234.567 |
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