Shikonin Induced Program Cell Death through Generation of Reactive Oxygen Species in Renal Cancer Cells

• Main Authors: Ming-Feng Tsai (Author), Shih-Ming Chen (Author), Ann-Zhi Ong (Author), Yi-Hsuan Chung (Author), Pei-Ni Chen (Author), Yi-Hsien Hsieh (Author), Yu-Ting Kang (Author), Li-Sung Hsu (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Shikonin mitigated tumor cell proliferation by elevating reactive oxygen species (ROS) levels. Herein, we investigated the effects of shikonin on renal cancer cell (RCC) cell proliferation. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay indicated that shikonin dose-dependen...