The long non-coding RNA GAS5 contributes to the suppression of inflammatory responses by inhibiting NF-κB activity

• Main Authors: Debora Curci (Author), Biljana Stankovic (Author), Nikola Kotur (Author), Letizia Pugnetti (Author), Vladimir Gasic (Author), Maurizio Romano (Author), Branka Zukic (Author), Giuliana Decorti (Author), Gabriele Stocco (Author), Marianna Lucafò (Author), Sonja Pavlovic (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionNuclear factor kappa B (NF-κB) is a key regulator of immune and inflammatory responses. Glucocorticoid drugs (GC) act through the glucocorticoid receptor (GR) as immunosuppressant also in pediatric patients inhibiting NF-κB activity. The long non-coding RNA GAS5 interacts with the GR, in...