Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1

• Main Authors: Jinling Zhou (Author), Yuanhe Wang (Author), Lizhu Zhang (Author), Qin Chen (Author), Xiaojun Zhu (Author), Peiyue Jiang (Author), Nan Jiang (Author), Wei Zhao (Author), Baohua Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In cervical cancer (CC), cisplatin resistance greatly restricts the application in clinical. Here, we report that engineered exosomes-mediated transfer of hsa-miR-320a overcomes chemoresistance in cervical cancer cells via targeting Myeloid Cell Leukemia Sequence 1 (MCL1). In DDP resistant CC tissue...