Plasmodium falciparum Drug Resistance Genes pfmdr1 and pfcrt In Vivo Co-Expression During Artemether-Lumefantrine Therapy

• Main Authors: M. Silva (Author), M. Malmberg (Author), S. D. Otienoburu (Author), A. Björkman (Author), B. Ngasala (Author), A. Mårtensson (Author), J. P. Gil (Author), M. I. Veiga (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Background: Artemisinin-based combination therapies (ACTs) are the global mainstay treatment of uncomplicated Plasmodium falciparum infections. PfMDR1 and PfCRT are two transmembrane transporters, associated with sensitivity to several antimalarials, found in the parasite food vacuole. Herein, we ex...