LRRC4 functions as a neuron-protective role in experimental autoimmune encephalomyelitis

• Main Authors: Yan Zhang (Author), Di Li (Author), Qiuming Zeng (Author), Jianbo Feng (Author), Haijuan Fu (Author), Zhaohui Luo (Author), Bo Xiao (Author), Huan Yang (Author), Minghua Wu (Author)
• Format: Book
• Published: BMC, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Leucine rich repeat containing 4 (LRRC4), also known as netrin-G ligand-2 (NGL-2), belongs to the superfamily of LRR proteins and serves as a receptor for netrin-G2. LRRC4 regulates the formation of excitatory synapses and promotes axon differentiation. Mutations in LRRC4 occur i...