AAV-Anti-miR-214 Prevents Collapse of the Femoral Head in Osteonecrosis by Regulating Osteoblast and Osteoclast Activities

• Main Authors: Cheng Wang (Author), Weijia Sun (Author), Shukuan Ling (Author), Yu Wang (Author), Xin Wang (Author), Haoye Meng (Author), Yuheng Li (Author), Xueling Yuan (Author), Jianwei Li (Author), Ruoxi Liu (Author), Dingsheng Zhao (Author), Qiang Lu (Author), Aiyuan Wang (Author), Quanyi Guo (Author), Shibi Lu (Author), Hua Tian (Author), Yingxian Li (Author), Jiang Peng (Author)
• Format: Book
• Published: Elsevier, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteonecrosis of the femoral head, an intractable but common disease that eventually triggers collapse of the femoral head, is characterized by increased osteoclast activity and markedly decreased osteoblast activity in the necrotic region of the femoral head. MicroRNA (miRNA)-214 (miR-214) may play...