Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA5m chelators
Abstract Background Fibroblast activation protein (FAP) is a proline selective serine protease that is overexpressed in tumor stroma and in lesions of many other diseases that are characterized by tissue remodeling. In 2014, a most potent FAP-inhibitor (referred to as UAMC1110) with low nanomolar FA...
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Main Authors: | , , , , , , , , , , , , , , |
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Format: | Book |
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SpringerOpen,
2020-07-01T00:00:00Z.
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A1234.567 |
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