PD-L1 Blockade Attenuated Sepsis-Induced Liver Injury in a Mouse Cecal Ligation and Puncture Model

• Principais autores: Weimin Zhu (Autor), Rui Bao (Autor), Xiaohua Fan (Autor), Tianzhu Tao (Autor), Jiali Zhu (Autor), Jiafeng Wang (Autor), Jinbao Li (Autor), Lulong Bo (Autor), Xiaoming Deng (Autor)
• Formato: Livro
• Publicado em: Hindawi Limited, 2013-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Liver plays a major role in hypermetabolism and produces acute phase proteins during systemic inflammatory response syndrome and it is of vital importance in host defense and bacteria clearance. Our previous studies indicated that programmed death-1 (PD-1) and its ligand programmed death ligand-1 (P...