In vitro and in vivo activity of a palladacycle complex on Leishmania (Leishmania) amazonensis.

• Main Authors: Carolina de Siqueira Paladi (Author), Isabella Aparecida Salerno Pimentel (Author), Simone Katz (Author), Rodrigo L O R Cunha (Author), Wagner Alves de Souza Judice (Author), Antonio C F Caires (Author), Clara Lúcia Barbiéri (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Antitumor cyclopalladated complexes with low toxicity to laboratory animals have shown leishmanicidal effect. These findings stimulated us to test the leishmanicidal property of one palladacycle compound called DPPE 1.2 on Leishmania (Leishmania) amazonensis, an agent of simple and diffu...