The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa

The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa

In mice, rats, dogs and humans, the growth and function of sebaceous glands and eyelid Meibomian glands depend on the ectodysplasin signalling pathway. Mutation of genes encoding the ligand EDA, its transmembrane receptor EDAR and the intracellular signal transducer EDARADD leads to hypohidrotic ect...

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Main Authors: Jorge del-Pozo (Author), Denis J. Headon (Author), James D. Glover (Author), Ali Azar (Author), Sonia Schuepbach-Mallepell (Author), Mahmood F. Bhutta (Author), Jon Riddell (Author), Scott Maxwell (Author), Elspeth Milne (Author), Pascal Schneider (Author), Michael Cheeseman (Author)
Format: Book
Published: The Company of Biologists, 2022-03-01T00:00:00Z.
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