Discovery and Characterization of the Key Constituents in Ginkgo biloba Leaf Extract With Potent Inhibitory Effects on Human UDP-Glucuronosyltransferase 1A1

• Päätekijät: Hui-Lin Pang (Tekijä), Guang-Hao Zhu (Tekijä), Qi-Hang Zhou (Tekijä), Chun-Zhi Ai (Tekijä), Ya-Di Zhu (Tekijä), Ping Wang (Tekijä), Tong-Yi Dou (Tekijä), Yang-Liu Xia (Tekijä), Hong Ma (Tekijä), Guang-Bo Ge (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Human UDP-glucuronosyltransferase 1A1 (hUGT1A1) is one of the most essential phase II enzymes in humans. Dysfunction or strong inhibition of hUGT1A1 may result in hyperbilirubinaemia and clinically relevant drug/herb-drug interactions (DDIs/HDIs). Recently, a high-throughput fluorescence-based assay...