IL-17A increases MHC class I expression and promotes T cell activation in papillary thyroid cancer patients with coexistent Hashimoto's thyroiditis

• Main Authors: Li-Tao Han (Author), Jia-Qian Hu (Author), Ben Ma (Author), Duo Wen (Author), Ting-Ting Zhang (Author), Zhong-Wu Lu (Author), Wen-Jun Wei (Author), Yu-Long Wang (Author), Yu WANG (Author), Tian Liao (Author), Qing-Hai Ji (Author)
• Format: Book
• Published: BMC, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The incidence of coexisting papillary thyroid cancer (PTC) and Hashimoto's thyroiditis (HT) is increasing. The impact of HT on PTC prognosis and its possible mechanism remains controversial. Interleukin-17A (IL-17A) has been reported to participate in the pathogenesis of mul...