Bioequivalence Analysis of Terazosin Hydrochloride Tablets Based on Parallel Artificial Membrane Permeability Analysis

• Main Authors: Jianzhao Niu (Author), Hanhan Huang (Author), Ming Ji (Author), Wenjing Zhang (Author), Yin Huang (Author), Lingyun Ma (Author), Baolian Wang (Author), Qian Liu (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parallel artificial membrane permeability analysis (PAMPA) is used to determine the permeability of compounds through concentrated negatively charged phospholipid bilayer barriers. We employed MacroFlux (a scaled-up version of PAMPA) to test the permeation rate of terazosin hydrochloride (TH) tablet...