C/EBPβ promotes the expression of atrophy‐inducing factors by tumours and is a central regulator of cancer cachexia

• Main Authors: Hamood AlSudais (Author), Rashida Rajgara (Author), Aisha Saleh (Author), Nadine Wiper‐Bergeron (Author)
• Formato: Livro
• Publicado em: Wiley, 2022-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background CCAAT/enhancer‐binding protein β (C/EBPβ) is a transcription factor whose high expression in human cancers is associated with tumour aggressiveness and poor outcomes. Most advanced cancer patients will develop cachexia, characterized by loss of skeletal muscle mass. In response t...