Use of humanised rat basophilic leukaemia cell line RS-ATL8 for the assessment of allergenicity of Schistosoma mansoni proteins.

• Main Authors: Daniel Wan (Author), Fernanda Ludolf (Author), Daniel G W Alanine (Author), Owen Stretton (Author), Eman Ali Ali (Author), Nafal Al-Barwary (Author), Xiaowei Wang (Author), Michael J Doenhoff (Author), Adriano Mari (Author), Colin M Fitzsimmons (Author), David W Dunne (Author), Ryosuke Nakamura (Author), Guilherme C Oliveira (Author), Marcos J C Alcocer (Author), Franco H Falcone (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parasite-specific IgE is thought to correlate with protection against Schistosoma mansoni infection or re-infection. Only a few molecular targets of the IgE response in S. mansoni infection have been characterised. A better insight into the basic mechanisms of anti-parasite immunity could be gained...