Dental effects of enzyme replacement therapy in case of childhood-type hypophosphatasia

Abstract Background Hypophosphatasia (HPP), a skeletal disease characterized by hypomineralization of bone and teeth, is caused by an ALPL gene mutation that leads to low activity of the tissue non-specific alkaline phosphatase enzyme. Although enzyme replacement therapy (ERT) was recently introduce...

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Bibliographic Details
Main Authors: Rena Okawa (Author), Kazuma Kokomoto (Author), Kazuhiko Nakano (Author)
Format: Book
Published: BMC, 2021-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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