Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling

• Main Authors: Bin Zhang (Author), Jingyi Zhang (Author), Chenyang Zhang (Author), Xuelian Zhang (Author), Jingxue Ye (Author), Shihuan Kuang (Author), Guibo Sun (Author), Xiaobo Sun (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetic cardiomyopathy (DCM) leads to heart failure and death in diabetic patients, no effective treatment is available. Notoginsenoside R1 (NGR1) is a novel saponin that is derived from Panax notoginseng and our previous studies have showed cardioprotective and neuroprotective effects of NGR1. How...