Antagonizing αvβ3 Integrin Improves Ischemia-Mediated Vascular Normalization and Blood Perfusion by Altering Macrophages

• Asıl Yazarlar: Yongjie Li (Yazar), Qian Gao (Yazar), Xin Shu (Yazar), Lamei Xiao (Yazar), Yan Yang (Yazar), Ningbo Pang (Yazar), Yulin Luo (Yazar), Jing He (Yazar), Liping Zhang (Yazar), Jianbo Wu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: αVβ3 integrin has been implicated in the physiological processes and pathophysiology of important angiogenesis-related disorders; however, the preclinical and clinical data on integrin αVβ3 antagonists have not demonstrated improved outcomes. Our goal was to test the hypothesis that inhi...